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Writer's pictureAbderrahim Benmoussa, phD

Underlying diseases in Covid-19, a systematic review and meta-analysis

Updated: Apr 6, 2020

Quality of evidence: B

 

Prevalence of Underlying Diseases in Hospitalized Patients With COVID-19: A Systematic Review and Meta-Analysis

 

Authors: Emami A et al.

Journal: Archives Academic Emergency Medicine

Objectives: Estimate the prevalence of underlying diseases in hospitalized COVIDs 19

Strength of evidence: Moderate ( only abstracts used for some studies, include studies of limited quality or low strength of evidence, only 10 articles, only from Chinese centers)

Methods/publication type: Meta-Analysis

  • Meta-Analysis

  • PubMed, Scopus, Web of Science, Google Scholar, Embase, The WHO, and CDC websites

  • Terms: [SARS-CoV-2 AND characteristics] OR, [2019-nCoV AND Characteristics] "OR" COVID-19 AND Comorbidities] OR [new coronavirus AND Characteristics AND Comorbidities] OR [Wuhan Coronavirus AND Characteristics AND Comorbidities] OR [Coronavirus AND characteristics AND Comorbidities]

  • Articles published until February 15, 2020.

  • All articles reporting clinical and epidemiological characteristics of patients hospitalized for COVID 19 (3,403 patients in total)

Highlights :

  • Hypertension, CVD, diabetes, tobacco, COPD, tumor (and in particular lung cancer), chronic renal failure are among the most frequent comorbidities in COVID-19 hospitalized patients

  • CVDs are the most prevalent co-morbidities.

The pooled prevalence of the most prevalent co-morbidities:

  • hypertension = 16.37% (CI 9510.15% -23.65%)

  • cardiovascular diseases (CVD) = 12.11% (95% CI 4.40% -22.75%),

  • smoking = 7.63% (95% CI 3.83% -12.43%)

  • diabetes = 7.87% (95% CI 6.57% -9.28%)

 

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