Clinical features of Covid-19, a multicentric cohort study

Quality of evidence: B-

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Clinical Characteristics of Coronavirus Disease 2019 in China

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Authors: Guan WJ et al

Journal: New-England Journal of Medicine

Objectives: Describing clinical features of patients with COVID-19 in Wuhan

Strength of evidence: Moderate (well-designed cohort study but only descriptive)

Methods/publication type: Multicentric cohort study

Highlights :

• The median age of infected patients, 47 years old, with 5% of severe forms and 2.3% of intubation

• Fever in less than half of non-hospitalized cases and cough present in 2/3 of cases

• Median incubation period = 4 days (IQR: 2-7)

• Bilateral ground-glass opacity in half of the cases, but 18% of cases without radio signs

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